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KMID : 0900920020260010025
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Korean journal of Animal Reproduction
2002 Volume.26 No. 1 p.25 ~ p.32
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Effect of Bisphenol A Administration on Semen Characteristic and Organ Weight in Mice
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Park Dong-Heon
Park Choon-Keun
Kim Choung-Ik
Cheong Hee-Tae
Yang Boo-Keun
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Abstract
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This study were performed to investigate the effect of Bisphenol A(BPA) administration on semen characteristic and body or organ weight in mice. In BPA administration for 15 days or 30 days, sperm concentration and viability were lower in group treated with BPA than in control group. The proportion of sperm abnormality were significantly(P＜0.05) increased in groups administrated with BPA for 15 or 30 days than in control group. The administration of BPA in mice didn′t affect the body and reproductive organ weight such as testis, epididymis, vasicular gland and coagulatin gland. The spleen weight were significantly affect, but liver and kidney weight were not affect in BPA administration groups for 15 days or 30 days This studies indicate that the short or long term BPA administration in mice were noxious effects on the semen characteristics and organ weight, but didn′t affect body weight and reproductive organs.
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KEYWORD
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Bispenol A, Endorcrine disruptors, Semen characteristics, Mouse
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